Mining The Cancer Genome Atlas (TCGA) Database to Identify Genotype Matched Tumor Suppressor microRNAs toward the Next Generation of Cancer Drugs
Targeting the hedgehog signalling pathway in triple negative breast cancer
Identification of a novel glucose oxidation agonist that selectively kills cancer cells
PP2A - a novel biomarker and therapeutic target for poor outcome breast cancer
Cell cycle checkpoint inhibition and cyclophosphamide is an effective combination therapy in a mouse model of paediatric medulloblastoma
The glucocorticoid receptor coordinately regulates BIM and BCL2 in paediatric acute lymphoblastic leukaemia cells
Establishing in vitro and in vivo models to develop novel therapeutic approaches for Diffuse Intrinsic Pontine Glioma.
Targeting mitochondrial function and the PI3K/AKT/mTOR pathway as a novel therapeutic approach in the treatment of Diffuse Intrinsic Pontine Glioma
Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA activation and transendothelial migration
Identification of CIP2A as a Prognostic Marker and a Therapeutic Target in Glioblastoma
Global Phosphoproteomic Mapping Reveals How Phosphatases Control Mitotic Exit And Maintain Genome Stability
High-throughput screening identifies new inhibitors of the multidrug transporter MRP4
MYCN coordinately regulates the entire polyamine pathway to maintain high polyamine levels in neuroblastoma
A comprehensive and systematic analysis of miRNA function in neuroblastoma
Novel approaches to targeting the tumour-stroma coalition in triple negative breast cancers
Molecular profiling to predict drug sensitivity or resistance in relapsed childhood cancer
Targeting copper metabolism in neuroblastoma using Dextran-Catechin
An 18-gene Myc activity signature for neuroblastoma and other Myc-driven cancers
Involvement of ATM in the recruitment of human telomerase to telomeres
Reactivating the p53 stress response to treat oesophageal cancer
Molecular diagnostics in pediatric (neuro-) onclology in the omics era
Identification of a novel compound that synergistically inhibits cell growth with BRAF inhibitor in BRAF wildtype and NRAS mutant melanoma cells
MEK inhibition and models of resistance in acute myeloid leukaemia.
The prorenin receptor as a novel therapeutic target for the treatment of endometrial cancer
A new cancer therapeutic that targets angiogenic vessels