The renin angiotensin system in endometrial cancer
The novel long non-coding RNA RP1X induces N-Myc protein stabilization, tumour cell proliferation and survival
Global Demethylation Increases XPC Expression and Overcomes Platinum Therapy Resistance in Melanoma
Increased density of somatic mutations at core promoters is linked to neutral selection and transcriptional activity
Systematic Identification of Ubiquitin Ligase Substrates
UBR5 Regulates Primary Cilia Formation via Interactions with Multiple Centriollar Proteins
Excessive activation of the Src-kinase HCK in the tumor stroma promotes progression of solid tumors
How to improve a good drug - Tales of the unexpected
Molecular Imaging: A Window into Cancer
A genome-wide, synthetic lethal screen for innate platinum-resistance genes in lung adenocarcinoma.
Tackling Pancreatic Cancer using a Novel Nanotechnology-siRNA Therapeutic
Transcriptional regulation of mammary gland lineage commitment by Inhibitor of Differentiation 4 (Id4)
Rational therapies and Moving Targets
Constraining healthcare expenditures and determining value for genomic medicine in oncology
Working together to catalyse the discovery of pioneer targets for cancer drug discovery: creating a new, more efficient ecosystem
Discovery of a small molecule TUBB3/βIII-tubulin modulator in lung cancer
THIOIMIDAZOLINE BASED COMPOUNDS REVERSE GLUCOCORTICOID RESISTANCE IN PAEDIATRIC ACUTE LYMPHOBLASTIC LEUKAEMIA
BIOLUMINESCENCE IMAGING ENHANCES ANALYSIS OF DRUG RESPONSE IN A PATIENT-DERIVED XENOGRAFT MODEL OF PAEDIATRIC ACUTE LYMPHOBLASTIC LEUKAEMIA
Discovery of CTx-0391034 a novel potent and selective inhibitor of PRMT5
TBA
DNA methylation of estrogen regulated enhancers defines endocrine sensitivity in breast cancer
Targeting Vascular Remodelling in Cancer
Overcoming resistance to therapies targeting oncogenes
Paediatric glioblastoma: unique targets in unique diseases
Biomarker-driven cancer therapy