Professor Richard Lock is an NHMRC Senior Research Fellow at Children’s Cancer Institute, UNSW Australia. He received his PhD in 1987 from the University of London, for research carried out at the Imperial Cancer Research Fund Laboratories. His postdoctoral research was carried at the University of Florida and the University of Louisville, USA. Upon relocation to Australia in 1998, he established the Leukaemia Biology Program at Children’s Cancer Institute. The principal focus of his research is in the development and utilisation of orthotopic patient-derived xenograft models of paediatric acute lymphoblastic leukaemia and acute myelogenous leukaemia to study the biology and treatment of the diseases. In 2005 he was the only Principal Investigator outside of the USA invited to participate in the NCI-funded Pediatric Preclinical Testing Program (PPTP), which has received continuous NCI funding since 2005. Professor Lock has published around 159 articles in peer-reviewed journals, and has been an invited speaker at many national and international conferences.